Endocrine Abstracts

Introduction: The coexistence of adrenal tumors (AT) in patients with neuroendocrine tumors (NETs) has not been extensively studied. The aim of our study was to investigate their prevalence and clinical significance in these patients.Materials and methods: We retrospectively studied 447 patients with NETs of all localizations, treated at our department between 2004 and 2012. Diagnosis was established pathohistologically, classification performed accordin...

IntroductionMerkel cell carcinoma-MCC) is a rare, aggressive, neuroendocrine skin tumor with a poor prognosis. Chemotherapy (CT) and/or local/locoregional radiotherapy (LRRT) are first-line MCC therapies, but disseminated/locally advanced MCCs often become resistant to this treatment. The use of programmed cell death receptor1/programmed cell death ligand 1 (PD-1/PD-L1) monoclonal antibodies is a new type of therapy for MCC. While PD-1 monoclonal antibod...